Sexenios de investigación: 4 (1996-2002; 2003-2008; 2009-2014; 2015-2020)
Número de tesis doctorales dirigidas en los últimos 10 años: 17
Citas totales (fuente Google Scholar): 10385
Promedio de citas/año durante los últimos 5 años (fuente Google Scholar): 908
Indice h (fuentes Web of Science/Scopus/GoogleScholar): 38/40/54
Número total de publicaciones JCR: 200
Artículos
- Gonçalves, Inês G.; García-Aznar, Jose Manuel. Neurorosettes: a novel computational modelling framework to investigate the Homer-Wright rosette formation in neuroblastoma. COMPUTATIONAL PARTICLE MECHANICS. 2024. DOI: 10.1007/s40571-023-00639-1
- Sainz de Mena, D.; Pérez, M. A.; García-Aznar, J. M. Exploring the potential of Physics-Informed Neural Networks to extract vascularization data from DCE-MRI in the presence of diffusion. MEDICAL ENGINEERING & PHYSICS. 2024. DOI: 10.1016/j.medengphy.2023.104092
- García-Gareta, Elena; Calderón Villalba, Alejandro; Alamán-Díez, Pilar; Gracia Costa, Carlos; Guerrero, Pedro Enrique; Mur, Carlota; Rueda Flores, Ana; Olivera Jurjo, Nerea; Sancho, Patricia; Pérez, María Ángeles; García-Aznar, José Manuel. Physico-chemical characterization of the tumour microenvironment of pancreatic ductal adenocarcinoma. EUROPEAN JOURNAL OF CELL BIOLOGY. 2024. DOI: 10.1016/j.ejcb.2024.151396
- Camacho-Gómez, Daniel; Movilla, Nieves; Borau, Carlos; Martín, Alejandro; Oñate Salafranca, Carmen; Pardo, Julián; Gómez-Benito, María José; García-Aznar, José Manuel. An agent-based method to estimate 3D cell migration trajectories from 2D measurements: Quantifying and comparing T vs CAR-T 3D cell migration. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE. 2024. DOI: 10.1016/j.cmpb.2024.108331
- Vercher-Martínez, Ana; Giner, Eugenio; Fuenmayor, F. Javier; García-Aznar, J. Manuel. The role of the interfaces and cross-links on the mechanical behavior of mineralized collagen fibrils. A numerical approach. ENGINEERING FRACTURE MECHANICS. 2024. DOI: 10.1016/j.engfracmech.2024.110440
- Hernández-Hatibi, Soraya; Guerrero, Pedro Enrique; García-Aznar, José Manuel; García-Gareta, Elena. Polydopamine interfacial coating for stable Tumor-on-a-Chip models: application for Pancreatic Ductal Adenocarcinoma. BIOMACROMOLECULES. 2024. DOI: 10.1021/acs.biomac.4c00551
- Garcia-Peiro, Jose I.; Guerrero-López, Paula; Hornos, Felipe; Hueso, Jose L.; Garcia-Aznar, J. Manuel; Santamaria, Jesus. The Pattern of Copper Release in Copper-Based Nanoparticles Regulates Tumor Proliferation and Invasiveness in 3D Culture Models. SMALL SCIENCE. 2024. DOI: 10.1002/smsc.202400206
- Hervas-Raluy, Silvia; Sainz-Demena, Diego; Gómez-Benito, Maria José; García-Aznar, José Manuel. Image-based biomarkers for engineering neuroblastoma patient-specific computational models. ENGINEERING WITH COMPUTERS. 2024. DOI: 10.1007/s00366-024-01964-6
- Sáenz Ezquerro, Carlos; Laspalas, Manuel; García Aznar, José Manuel; Crespo Miñana, Cristina. Monitoring interactions through molecular dynamics simulations: effect of calcium carbonate on the mechanical properties of cellulose composites. CELLULOSE. 2023. DOI: 10.1007/s10570-022-04902-1
- Garcia-Aznar, Jm. Mechanotherapy as an alternative for cancer treatment. PHYSICS OF LIFE REVIEWS. 2023. DOI: 10.1016/j.plrev.2023.10.007
- Pele, Karinna Georgiana; Amaveda, Hippolyte; Mora, Mario; Marcuello, Carlos; Lostao, Anabel; Alamán-Díez, Pilar; Pérez-Huertas, Salvador; Pérez, María Ángeles; García-Aznar, José Manuel; García-Gareta, Elena. Hydrocolloids of egg white and gelatin as a platform for hydrogel-based tissue engineering. GELS. 2023. DOI: 10.3390/gels9060505
- Alamán-Díez, P.; Borau, C.; Guerrero, P. E.; Amaveda, H.; Mora, M.; Fraile, J. M.; García-Gareta, E.; García-Aznar, J. M.; Pérez, M. Á. Collagen-laponite nanoclay hydrogels for tumor spheroid growth. BIOMACROMOLECULES. 2023. DOI: 10.1021/acs.biomac.3c00257
- Camacho-Gomez, Daniel; Sorzabal-Bellido, Ioritz; Ortiz-De-Solorzano, Carlos; García-Aznar, José Manuel; Gómez-Benito, María José. A hybrid physics-based and data-driven framework for cellular biological systems: Application to the morphogenesis of organoids. ISCIENCE. 2023. DOI: 10.1016/j.isci.2023.107164
- Borau, C.; Wertheim, K.Y.; Hervas-Raluy, S.; Sainz-Demena, D.; Walker, D.; Chisholm, R.; Richmond, P.; Varella, V.; Viceconti, M.; Montero, A.; Gregori-Puigjané, E.; Mestres, J.; Kasztelnik, M.; García-Aznar, J.M. A multiscale orchestrated computational framework to reveal emergent phenomena in neuroblastoma. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE. 2023. DOI: 10.1016/j.cmpb.2023.107742
- Juste-Lanas, Yago; Hervás-Raluy, Silvia; García-Aznar, José Manuel; González-Loyola, Alejandra. Fluid flow to mimic organ function in 3D in vitro models. APL BIOENGINEERING. 2023. DOI: 10.1063/5.0146000
- Juma, Victor Ogesa; Sainz-Demena, Diego; Sánchez, María Teresa; García-Aznar, José Manuel. Effects of tumour heterogeneous properties on modelling the transport of radiative particles. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING. 2023. DOI: 10.1002/cnm.3760
- Juste-Lanas, Y.; Díaz-Valdivia, N.; Llorente, A.; Ikemori, R.; Bernardo, A.; Arshakyan, M.; Borau, C.; Ramírez, J.; Ruffinelli, J. C.; Nadal, E.; Reguart, N.; García-Aznar, J. M.; Alcaraz, J. 3D collagen migration patterns reveal a SMAD3-dependent and TGF-ß1-independent mechanism of recruitment for tumour-associated fibroblasts in lung adenocarcinoma. BRITISH JOURNAL OF CANCER. 2023. DOI: 10.1038/s41416-022-02093-x
- Pérez-Benito, Ángela; Huerta-López, Carla; Alegre-Cebollada, Jorge; García-Aznar, José Manuel; Hervas-Raluy, Silvia. Computational modelling of the mechanical behaviour of protein-based hydrogels. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2023. DOI: 10.1016/j.jmbbm.2023.105661
- Gonçalves, Inês G.; García-Aznar, José Manuel. Hybrid computational models of multicellular tumour growth considering glucose metabolism. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL. 2023. DOI: 10.1016/j.csbj.2023.01.044
- Sáenz Ezquerro, Carlos; Laspalas, Manuel; García Aznar, José Manuel; Castelar Ariza, Susana; Chiminelli, Agustín. Molecular modelling of graphene nanoribbons on the effect of porosity and oxidation on the mechanical and thermal properties. JOURNAL OF MATERIALS SCIENCE. 2023. DOI: 10.1007/s10853-023-08810-y
- Hervas-Raluy, Silvia; Wirthl, Barbara; Guerrero, Pedro E.; Robalo Rei, Gil; Nitzler, Jonas; Coronado, Esther; Font de Mora Sainz, Jaime; Schrefler, Bernhard A.; Gomez-Benito, Maria Jose; Garcia-Aznar, Jose Manuel; Wall, Wolfgang A. Tumour growth: An approach to calibrate parameters of a multiphase porous media model based on in vitro observations of Neuroblastoma spheroid growth in a hydrogel microenvironment. COMPUTERS IN BIOLOGY AND MEDICINE. 2023. DOI: 10.1016/j.compbiomed.2023.106895
- Gonçalves, Ines G.; Hormuth, David A.; Prabhakaran; Sandhya; Phillips, Caleb M.; García-Aznar, José Manuel PhysiCOOL: A generalized framework for model Calibration and Optimization Of modeLing projects. GIGABYTE. 2023. DOI: 10.46471/gigabyte.77
- Movilla, Nieves; Gonçalves, Inês G; Borau, Carlos; García-Aznar, Jose Manuel. A novel integrated experimental and computational approach to unravel fibroblast motility in response to chemical gradients in 3D collagen matrices. INTEGRATIVE BIOLOGY (CAMBRIDGE). 2023. DOI: 10.1093/intbio/zyad002
- Clavaín, L.; Fernández-Pisonero, I.; Movilla, N.; Lorenzo-Martín, L. F.; Nieto, B.; Abad, A.; García-Navas, R.; Llorente-González, C.; Sánchez-Martín, M.; Vicente-Manzanares, M.; Santos, E.; Alarcón, B.; García Aznar, J. M.; Dosil, M.; Bustelo, X. R. Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors. ONCOGENE. 2023. DOI: 10.1038/s41388-022-02563-9
- Hervas-Raluy, Silvia; Sainz de Mena, Diego; Gómez Benito, Mª José; García-Aznar, José Manuel. Herramienta de apoyo para cáncer pediátrico. JORNADA DE JÓVENES INVESTIGADORES DEL I3A. 2022. DOI: 10.26754/jjii3a.20226993
- Pérez-Rodríguez, Sandra; Borau, Carlos; García-Aznar, José Manuel; Gonzalo-Asensio, Jesús. A microfluidic-based analysis of 3D macrophage migration after stimulation by Mycobacterium, Salmonella and Escherichia. BMC MICROBIOLOGY. 2022. DOI: 10.1186/s12866-022-02623-w
- Beltrán, Gabriel; Navajas, Daniel; García-Aznar, José Manuel. Mechanical modeling of lung alveoli: from macroscopic behaviour to cell mechano-sensing at microscopic level. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2022. DOI: 10.1016/j.jmbbm.2021.105043
- Melo Quintela, Bárbara De; Hervás Raluy, Silvia; García Aznar, José Manuel; Walker, Dawn; Wertheim, Kenneth Y.; Viceconti, Marco. A theoretical analysis of the scale separation in a model to predict solid tumour growth. JOURNAL OF THEORETICAL BIOLOGY. 2022. DOI: 10.1016/j.jtbi.2022.111173
- Merino Casallo, Francisco; Gomez Benito, Maria Jose; Hervas Raluy, Silvia; Garcia-Aznar, Jose Manuel. Unravelling cell migration: defining movement from the cell surface. CELL ADHESION & MIGRATION. 2022. DOI: 10.1080/19336918.2022.2055520
- García Gareta, E.; Pérez, M. Á.; García Aznar, J. M. Decellularization of tumours: A new frontier in tissue engineering. JOURNAL OF TISSUE ENGINEERING. 2022. DOI: 10.1177/20417314221091682
- Camacho-Gómez, Daniel; García-Aznar, José Manuel; Gómez-Benito, María José A 3D multi-agent-based model for lumen morphogenesis: the role of the biophysical properties of the extracellular matrix. ENGINEERING WITH COMPUTERS. 2022. DOI: 10.1007/s00366-022-01654-1
- Saenz Ezquerro, Carlos ; Garcia Aznar, Jose Manuel ; Laspalas, Manuel. Prediction of the structure and mechanical properties of polycaprolactone-silica nanocomposites and the interphase region by molecular dynamics simulations: the effect of PEGylation. SOFT MATTER. 2022. DOI: 10.1039/d1sm01794b
- Juste-Lanas, Yago; Guerrero, Pedro E.; Camacho-Gomez, Daniel; Hervas-Raluy, Silvia; García-Aznar, J.M.; Gómez-Benito, María José. Confined cell migration and asymmetric hydraulic environments to evaluate the metastatic potential of cancer cells. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME. 2022. DOI: 10.1115/1.4053143
- Aparicio-Yuste, R.; Serrano-Alcalde, F.; Muenkel, M.; Garcia-Aznar, J.; Bastounis, E. E.; Gomez-Benito, M. Computational modelling of epithelial cell monolayers during infection with Listeria monocytogenes. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2022. DOI: 10.1016/j.cma.2022.115477
- Sainz-Demena, Diego; Ye, Wenfeng; Pérez, María Ángeles; García-Aznar, José Manuel A finite element based optimization algorithm to include diffusion into the analysis of DCE-MRI. ENGINEERING WITH COMPUTERS. 2022. DOI: 10.1007/s00366-022-01667-w
- Kondylakis, Haridimos; Ciarrocchi, Esther; Cerda-Alberich, Leonor; Chouvarda, Ioanna; Fromont, Lauren A.; Garcia-Aznar, Jose Manuel; Kalokyri, Varvara; Kosvyra, Alexandra; Walker, Dawn; Yang, Guang; Neri, Emanuele. Position of the AI for Health Imaging (AI4HI) network on metadata models for imaging biobanks. EUROPEAN RADIOLOGY EXPERIMENTAL. 2022. DOI: 10.1186/s41747-022-00281-1
- Mcevoy, E.; Sneh, T.; Moeendarbary, E.; Javanmardi, Y.; Efimova, N.; Yang, C.; Marino-Bravante, G. E.; Chen, X.; Escribano, J.; Spill, F.; Garcia-Aznar, J. M.; Weeraratna, A. T.; Svitkina, T. M.; Kamm, R. D.; Shenoy, V. B. Feedback between mechanosensitive signaling and active forces governs endothelial junction integrity. NATURE COMMUNICATIONS. 2022. DOI: 10.1038/s41467-022-34701-y
- Sainz-Demena, Diego; García-Aznar, José Manuel; Pérez, María Ángeles; Borau, Carlos. Im2mesh: A Python Library to Reconstruct 3D Meshes from Scattered Data and 2D Segmentations, Application to Patient-Specific Neuroblastoma Tumour Image Sequences. APPLIED SCIENCES (SWITZERLAND). 2022. DOI: 10.3390/app122211557
- Merino Casallo, F.; Gómez Benito, M. J.; Martínez Cantín, R.; García Aznar, J. M. A mechanistic protrusive-based model for 3D cell migration. EUROPEAN JOURNAL OF CELL BIOLOGY. 2022. DOI: 10.1016/j.ejcb.2022.151255
- Pérez-Rodríguez, S.; García-Aznar, J.M.; Gonzalo-Asensio, J. Microfluidic devices for studying bacterial taxis, drug testing and biofilm formation. MICROBIAL BIOTECHNOLOGY. 2021. DOI: 10.1111/1751-7915.13775
- Serrano-Alcalde, F.; García-Aznar, J.M.; Gómez-Benito, M.J. Cell biophysical stimuli in lobodopodium formation: a computer based approach. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2021. DOI: 10.1080/10255842.2020.1836622
- Silberschmidt, V.V.; Garcia Aznar, J.M. Damage and fracture of biological and biomedical materials. ENGINEERING FRACTURE MECHANICS. 2021. DOI: 10.1016/j.engfracmech.2020.107067
- García-Aznar, José Manuel; Nasello, Gabriele; Hervas-Raluy, Silvia; Pérez Ansón, María de los Ángeles; Gómez-Benito, María José. Multiscale modeling of bone tissue Mechanobiology. BONE. 2021. DOI: 10.1016/j.bone.2021.116032
- Kainz H.; Killen B.A.; Van Campenhout A.; Desloovere K.; García Aznar J.M.; Shefelbine S.; Jonkers I. ESB Clinical Biomechanics Award 2020: Pelvis and hip movement strategies discriminate typical and pathological femoral growth – Insights gained from a multi-scale mechanobiological modelling framework. CLINICAL BIOMECHANICS. 2021. DOI: 10.1016/j.clinbiomech.2021.105405
- Bastounis, E.E.; Serrano-Alcalde, F.; Radhakrishnan, P.; Engström, P.; Gómez-Benito, M.J.; Oswald, M.S.; Yeh, Y.T.; Smith, J.G.; Welch, M.D.; García-Aznar, J.M.; Theriot, J.A. Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells. DEVELOPMENTAL CELL. 2021. DOI: 10.1016/j.devcel.2021.01.012
- Hervás Raluy, Silvia; Gómez Benito, María José; Borau Zamora, Carlos; Condor, Mar; García Aznar, José Manuel. A new 3d finite element-based approach for computing cell surface tractions assuming nonlinear conditions. PLOS ONE. 2021. DOI: 10.1371/journal.pone.0249018
- Pérez Rodríguez, S.; Huang, S.A.; Borau, C.; García Aznar, J.M.; Polacheck, W.J. Microfluidic model of monocyte extravasation reveals the role of hemodynamics and subendothelial matrix mechanics in regulating endothelial integrity. BIOMICROFLUIDICS. 2021. DOI: 10.1063/5.0061997
- Goncalves, Ig; Garcia-Aznar, Jm. Extracellular matrix density regulates the formation of tumour spheroids through cell migration. PLOS COMPUTATIONAL BIOLOGY. 2021. DOI: 10.1371/journal.pcbi.1008764
- Anguiano, María; Morales, Xabier; Castilla, Carlos; Rodríguez, Pena, Alejandro; Ederra, Cristina; Martínez, Martín; Ariz, Mikel; Esparza, Maider; Amaveda, Hippolyte; Mora, Mario; Movilla, Nieves; García, Aznar, José Manuel; Cortés-Domínguez, Iván; Ortiz de Solorzano, Carlos. The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion. PLOS ONE. 2020. DOI: 10.1371/journal.pone.0220019
- Nieto, A.; Escribano, J.; Spill, F.; Garcia-Aznar, J.M.; Gomez-Benito, M.J. Finite element simulation of the structural integrity of endothelial cell monolayers: A step for tumor cell extravasation. ENGINEERING FRACTURE MECHANICS. 2020. DOI: 10.1016/j.engfracmech.2019.106718
- Martí-Bonmatí, L.; Alberich-Bayarri, Á.; Ladenstein, R.; Blanquer, I.; Segrelles, J.D.; Cerdá-Alberich, L.; Gkontra, P.; Hero, B.; García-Aznar, J.M.; Keim, D.; Jentner, W.; Seymour, K.; Jiménez-Pastor, A.; González-Valverde, I.; Martínez de las Heras, B.; Essiaf, S.; Walker, D.; Rochette, M.; Bubak, M.; Mestres, J.; Viceconti, M.; Martí-Besa, G.; Cañete, A.; Richmond, P.; Wertheim, K.Y.; Gubala, T.; Kasztelnik, M.; Meizner, J.; Nowakowski, P.; Gilpérez, S.; Suárez, A.; Aznar, M.; Restante, G.; Neri, E. PRIMAGE project: predictive in silico multiscale analytics to support childhood cancer personalised evaluation empowered by imaging biomarkers. EUROPEAN RADIOLOGY EXPERIMENTAL. 2020. DOI: 10.1186/s41747-020-00150-9
- Movilla, Nieves; Valero, Clara; Borau Zamora, Carlos; García-Aznar, José Manuel. Matrix degradation regulates osteoblast protrusion dynamics and individual migration. INTEGRATIVE BIOLOGY (CAMBRIDGE). 2020. DOI: 10.1093/intbio/zyz035
- Sánchez, María Teresa; Pérez, María Ángeles; García-Aznar, José Manuel. The role of fluid flow on bone mechanobiology: mathematical modeling and simulation. COMPUTATIONAL GEOSCIENCES. 2020. DOI: 10.1007/s10596-020-09945-6
- Hervás Raluy, Silvia; Gomez-Benito, Mªjose; Borau-Zamora, Carlos; Garcia-Aznar, Jose Manuel. Are the Cells Stronger than we Think?. JORNADA DE JÓVENES INVESTIGADORES DEL I3A. 2020. DOI: 10.26754/jjii3a.4887
- Nasello, Gabriele; Alamán-Díez, Pilar; Schiavi, Jessica; Pérez, María Ángeles; Mcnamara, Laoise ; García-Aznar, José Manuel. Primary Human Osteoblasts Cultured in a 3D Microenvironment Create a Unique Representative Model of Their Differentiation Into Osteocytes. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 2020. DOI: 10.3389/fbioe.2020.00336
- Kainz, H.; Killen, B.A.; Wesseling, M.; Perez-Boerema, F.; Pitto, L.; Garcia Aznar, J.M.; Shefelbine, S.; Jonkers, I. A multi-scale modelling framework combining musculoskeletal rigid-body simulations with adaptive finite element analyses, to evaluate the impact of femoral geometry on hip joint contact forces and femoral bone growth. PLOS ONE. 2020. DOI: 10.1371/journal.pone.0235966
- Calvo-Gallego, J.L.; Pivonka, P.; Garcia-Aznar, J.M.; Martinez-Reina, J. A novel algorithm to resolve lack of convergence and checkerboard instability in bone adaptation simulations using non-local averaging. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING. 2020. DOI: 10.1002/cnm.3419
- Nasello, Gabriele; Vautrin, Antoine; Pitocchi, Jonathan; Wesseling, Mariska; Kuiper, Jan Herman; Pérez Ansón, María de los Ángeles;García Aznar, José Manuel. Mechano-driven regeneration predicts response variations in large animal model based on scaffold implantation site and individual mechano-sensitivity. BONE. 2020. DOI: 10.1016/j.bone.2020.115769
- Bastounis, E.E.; Radhakrishnan, P.; Engstrom, P.; Alcalde, F.; Gómez Benito, María; Gacía Aznar, J.M.; Welch, M.; Theriot, J. Mechanically-Driven Cellular Competition Promotes the Collective Extrusion of Bacteria-Infected Epithelial Cells. BIOPHYSICAL JOURNAL. 2020. DOI: 10.1016/j.bpj.2019.11.1147
- Cóndor, M.; Mark, C.; Gerum, R.C.; Grummel, N.C.; Bauer, A.; García-Aznar, J.M.; Fabry, B. Breast cancer cells adapt contractile forces to overcome steric hindrance. BIOPHYSICAL JOURNAL. 2019. DOI: 10.1016/j.bpj.2019.02.029
- Hervas-Raluy, S.; Garcia-Aznar, J.M.; Gomez-Benito, M.J. Modelling actin polymerization: the effect on confined cell migration. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2019. DOI: 10.1007/s10237-019-01136-2
- Olivares, Vanesa; Cóndor, Mar; Amo, Cristina Del; Asín, Jesús; Borau, Carlos; García-Aznar, José Manuel. Image-based characterization of 3D collagen networks and the effect of embedded cells. MICROSCOPY AND MICROANALYSIS. 2019. DOI: 10.1017/S1431927619014570
- Jorba, Ignasi; Beltrán, Gabriel; Falcones, Bryan; Suki, Béla; Farré, Ramón; García-Aznar, José Manuel; Navajas, Daniel. Nonlinear elasticity of the lung extracellular microenvironment is regulated by macroscale tissue strain. ACTA BIOMATERIALIA. 2019. DOI: 10.1016/j.actbio.2019.05.023
- Escribano, J.; Chen, M.B.; Moeendarbary, E.; Cao, X.; Shenoy, V.; Garcia-Aznar, J.M.; Kamm, R.D.; Spill, F. Balance of mechanical forces drives endothelial gap formation and may facilitate cancer and immune-cell extravasation. PLOS COMPUTATIONAL BIOLOGY. 2019. DOI: 10.1371/journal.pcbi.1006395
- Cóndor, M; García-Aznar, J.M. An iterative finite element-based method for solving inverse problems in traction force microscopy. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE. 2019. DOI: 10.1016/j.cmpb.2019.105056
- Gómez-Benito, M.J.; Valero, C.; García-Aznar, J.M.; Javierre, E. Computational modelling of wound healing insights to develop new treatments. COMPUTATIONAL METHODS IN APPLIED SCIENCES. 2019. DOI: 10.1007/978-3-030-15372-4_1
- Movilla, N.; Borau, C.; Valero, C.; García-Aznar, J.M. Degradation of extracellular matrix regulates osteoblast migration: A microfluidic-based study. BONE. 2018. DOI: 10.1016/j.bone.2017.10.025
- González-Valverde, I.; García-Aznar, J.M. Mechanical modeling of collective cell migration: An agent-based and continuum material approach. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2018. DOI: 10.1016/j.cma.2018.03.036
- del Amo, C.; Olivares, V.; Cóndor, M.; Blanco, A.; Santolaria, J.; Asín, J.; Borau, C.; García-Aznar, J.M. Matrix architecture plays a pivotal role in 3D osteoblast migration: The effect of interstitial fluid flow. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2018. DOI: 10.1016/j.jmbbm.2018.04.007
- Escribano, J.; Sunyer, R.; Sánchez, M.T.; Trepat, X.; Roca-Cusachs, P.; García-Aznar, J.M. A hybrid computational model for collective cell durotaxis. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2018. DOI: 10.1007/s10237-018-1010-2
- Merino-Casallo, F.; Gomez-Benito, M.J.; Juste-Lanas, Y.; Martinez-Cantin, R.; Garcia-Aznar, J.M. Integration of in vitro and in silico Models Using Bayesian Optimization With an Application to Stochastic Modeling of Mesenchymal 3D Cell Migration. FRONTIERS IN PHYSIOLOGY. 2018. DOI: 10.3389/fphys.2018.01246
- Valero, C.; Amaveda, H.; Mora, M.; García-Aznar, J.M. Combined experimental and computational characterization of crosslinked collagen-based hydrogels. PLOS ONE. 2018. DOI: 10.1371/journal.pone.0195820
- González-Valverde, I.; García-Aznar, J.M. An agent-based and FE approach to simulate cell jamming and collective motion in epithelial layers. COMPUTATIONAL PARTICLE MECHANICS. 2018. DOI: 10.1007/s40571-018-0199-2
- Pérez-Rodríguez, S.; Tomás-González, E.; García-Aznar, J.M. 3D cell migration studies for chemotaxis on microfluidic-based chips: A comparison between cardiac and dermal fibroblasts. BIOENGINEERING. 2018. DOI: 10.3390/bioengineering5020045
- Plou, J.; Juste-Lanas, Y.; Olivares, V.; del Amo, C.; Borau, C.; García-Aznar, J.M. From individual to collective 3D cancer dissemination: roles of collagen concentration and TGF-ß. SCIENTIFIC REPORTS (NATURE PUBLISHING GROUP). 2018. DOI: 10.1038/s41598-018-30683-4
- Sánchez, M.T.; García Aznar, J.M. Modeling Confined Cell Migration Mediated by Cytoskeleton Dynamics. COMPUTATION. 2018. DOI: 10.3390/computation6020033
- Cóndor, Mar; Rüberg, Thomas; Borau Zamora, Carlos; Piles, Joan; García-Aznar, José Manuel. A web-based application for automated quantification of chemical gradients induced in microfluidic devices. COMPUTERS IN BIOLOGY AND MEDICINE. 2018. DOI: 10.1016/j.compbiomed.2018.02.001
- Ribeiro, F.O.; Gómez-Benito, M.J.; Folgado, J.; Fernandes, P.R.; García-Aznar, J.M. Computational model of mesenchymal migration in 3D under chemotaxis. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2017. DOI: 10.1080/10255842.2016.1198784
- Garijo Millán, Noelia; Verdonschotb, Nico; Engelborghsd, Koen ; García-Aznar, Jose Manuel; Pérez, Mª Angeles. Subject-specific musculoskeletal loading of the tibia: Computational load estimation. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2017. DOI: 10.1016/j.jmbbm.2016.08.026
- Fernández, J.R.; García-Aznar, J.M.; Masid, M. Numerical analysis of an osteoconduction model arising in bone-implant integration. ZAMM-ZEITSCHRIFT FUR ANGEWANDTE MATHEMATIK UND MECHANIK. 2017. DOI: 10.1002/zamm.201500234
- Amo Mateos, Cristina Del; Borau, Carlos; Movilla, Nieves; Asín, Jesús; García-Aznar, José Manuel Quantifying 3D chemotaxis in microfluidic-based chips with step gradients of collagen hydrogel concentrations. INTEGRATIVE BIOLOGY (CAMBRIDGE). 2017. DOI: 10.1039/c7ib00022g
- Urrea, L.; Segura-Feliu, M.; Masuda-Suzukake, M.; Hervera, A.; Pedraz, L.; Garcia Aznar, J.M.; Vila, M.; Samitier, J.; Torrents, E.; Ferrer, I.; Gavín, R.; Hagesawa, M.; del Río, J.A. Involvement of Cellular Prion Protein in a-Synuclein Transport in Neurons. MOLECULAR NEUROBIOLOGY. 2017. DOI: 10.1007/s12035-017-0451-4
- Anguiano, M.; Castilla, C.; Maška, M.; Ederra, C.; Peláez, R.; Morales, X.; Muñoz-Arrieta, G.; Mujika, M.; Kozubek, M.; Muñoz-Barrutia, A.; Rouzaut, A.; Arana, S.; Garcia-Aznar, J.; Ortiz-De-Solorzano, C. Characterization of three-dimensional cancer cell migration in mixed collagen-Matrigel scaffolds using microfluidics and image analysis. PLOS ONE. 2017. DOI: 10.1371/journal.pone.0171417
- Oria, R.; Wiegand, T.; Escribano, J.; Elosegui-Artola, A.; Uriarte, J.J.; Moreno-Pulido, C.; Platzman, I.; Delcanale, P.; Albertazzi, L.; Navajas, D.; Trepat, X.; García-Aznar, J.M.; Cavalcanti-Adam, E.A.; Roca-Cusachs, P. Force loading explains spatial sensing of ligands by cells. NATURE. 2017. DOI: 10.1038/nature24662
- Serrano-Alcalde, F.; García-Aznar, J.M.; Gómez-Benito, M.J. The role of nuclear mechanics in cell deformation under creeping flows. JOURNAL OF THEORETICAL BIOLOGY. 2017. DOI: 10.1016/j.jtbi.2017.07.028
- Urrea, L.; Segura-Feliu, M.; Masuda-Suzukake, M.; Hervera, A.; Pedraz, L.; García-Aznar, J.M.; Vila, M.; Samitier, J.; Torrents, E.; Ferrer, I.; Gavín, R.; Hagesawa, M.; del Río, J.A. Erratum to: Involvement of Cellular Prion Protein in a-Synuclein Transport in Neurons. MOLECULAR NEUROBIOLOGY. 2017. DOI: 10.1007/s12035-017-0553-z
- Berli, M.; Borau, C.; Decco, O.; Adams, G.; Cook, R. B.; García Aznar, J. M.; Zioupos, P. Localized tissue mineralization regulated by bone remodelling: A computational approach. PLOS ONE. 2017. DOI: 10.1371/journal.pone.0173228
- González-Valverde, I.; García-Aznar, J. M. A hybrid computational model to explore the topological characteristics of epithelial tissues. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING. 2017. DOI: 10.1002/cnm.2877
- Cóndor, M.; Steinwachs, J.; Mark, C.; García-Aznar, J.M.; Fabry, B. Traction force microscopy in 3-dimensional extracellular matrix networks. CURRENT PROTOCOLS IN CELL BIOLOGY. 2017. DOI: 10.1002/cpcb.24
- Cóndor, M.; García-Aznar, J. M. A phenomenological cohesive model for the macroscopic simulation of cell-matrix adhesions. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2017. DOI: 10.1007/s10237-017-0883-9
- Rüberg, Thomas; García Aznar, José Manuel. Numerical simulation of solid deformation driven by creeping flow using an immersed finite element method. ADVANCED MODELING AND SIMULATION IN ENGINEERING SCIENCES. 2016. DOI: 10.1186/s40323-016-0061-0
- García-Aznar, J. M.;Valero, C.;Gómez-Benito, M. J.;Javierre, E. Insights to regenerate materials: Learning from nature. SMART MATERIALS & STRUCTURES. 2016. DOI: 10.1088/0964-1726/25/8/084001
- González-Valverde, I.;Semino, C.;García-Aznar, J. M. Phenomenological modelling and simulation of cell clusters in 3D cultures. COMPUTERS IN BIOLOGY AND MEDICINE. 2016. DOI: 10.1016/j.compbiomed.2016.08.019
- Sunyer, Raimon; Conte, Vito; Escribano, Jorge; Elosegui-Artola, Alberto; Labernadie, Anna; Valon, Léo; Navajas, Daniel; García-Aznar, José Manuel; Muñoz, José J.; Roca-Cusachs, Pere; Trepat, Xavier. Collective cell durotaxis emerges from long-range intercellular force transmission. SCIENCE. 2016. DOI: 10.1126/science.aaf7119
- Garcia Aznar, Jose Manuel; Valero, Clara; Borau Zamora, Carlos; Garijo, Noelia. Computational mechano-chemo-biology: a tool for the design of tissue scaffolds. BIOMANUFACTURING REVIEWS. 2016. DOI: 10.1007/s40898-016-0002-1
- Valero, C.; Navarro, B.; Navajas, D.; García-Aznar, J. M. Finite element simulation for the mechanical characterization of soft biological materials by atomic force microscopy. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2016. DOI: 10.1016/j.jmbbm.2016.05.006
- Ru¨berg, Thomas; Cirak, Fehmi; García Aznar, José Manuel. An unstructured immersed finite element method for nonlinear solid mechanics. ADVANCED MODELING AND SIMULATION IN ENGINEERING SCIENCES. 2016. DOI: 10.1186/s40323-016-0077-5
- del Amo, C.; Borau, C.; Gutiérrez, R.; Asín, J.; García-Aznar, J.M. Quantification of angiogenic sprouting under different growth factors in a microfluidic platform. JOURNAL OF BIOMECHANICS. 2016. DOI: 10.1016/j.jbiomech.2015.10.026
- Alierta, J. A.; Pérez, M. A.; Seral, B.; García-Aznar, J. M. Biomechanical assessment and clinical analysis of different intramedullary nailing systems for oblique fractures. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2016. DOI: 10.1080/10255842.2015.1125473
- Valero, C; Javierre, E; García-Aznar, Jm; Gómez-Benito, Mj; Menzel, A. Modeling of anisotropic wound healing. JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS. 2015. DOI: 10.1016/j.jmps.2015.03.009
- Moreno-Arotzena , Oihana ; Meier, Johann G; del Amo, Cristina; García-Aznar, José Manuel. Characterization of Fibrin and Collagen Gels for Engineering Wound Healing Models. MATERIALS. 2015. DOI: 10.3390/ma8041636
- Ribeiro, F.O.; Gómez-Benito, M.J.; Folgado, J.; Fernandes, P.R.; García-Aznar, J.M. In silico mechano-chemical model of bone healing for the regeneration of critical defects: The effect of BMP-2. PLOS ONE. 2015. DOI: 10.1371/journal.pone.0127722
- Moreno-Arotzena, O.; Borau, C.; Movilla, N.; Vicente-Manzanares, M.; García-Aznar, J.M. Fibroblast migration in 3D is controlled by haptotaxis in a non-muscle myosin II-dependent manner. ANNALS OF BIOMEDICAL ENGINEERING. 2015. DOI: 10.1007/s10439-015-1343-2
- Valero, C.; Javierre, E.; García-Aznar, J. M.; Menzel, A.; Gómez-Benito, M. J. Challenges in the Modeling of Wound Healing Mechanisms in Soft Biological Tissues. ANNALS OF BIOMEDICAL ENGINEERING. 2015. DOI: 10.1007/s10439-014-1200-8
- Escribano, J.; Sánchez, M.T.; García-Aznar, J.M. Modeling the formation of cell-matrix adhesions on a single 3D matrix fiber. JOURNAL OF THEORETICAL BIOLOGY. 2015. DOI: 10.1016/j.jtbi.2015.07.015
- Garijo, N.; Martinez, J.; Garcia Aznar, J.M.; Perez, M.A. Computational evaluation of different numerical tools for the prediction of proximal femur loads form bone morphology. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2014. DOI: 10.1016/j.cma.2013.10.005
- Garijo, N.; Fernández, J. R.; Pérez, M. A.; García-Aznar, J. M. Numerical stability and convergence analysis of bone remodeling model. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2014. DOI: 10.1016/j.cma.2013.12.014
- Martínez-Reina, J.; Reina, I.; Domínguez, J.; García-Aznar, J. M. A bone remodelling model including the effect of damage on the steering of BMUs. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2014. DOI: 10.1016/j.jmbbm.2013.12.025
- Mohaghegh, K.; Pérez, M. A.; García-Aznar, J. M. Accelerating numerical simulations of strain-adaptive bone remodeling predictions. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2014. DOI: 10.1016/j.cma.2014.02.003
- Prokharau, P. A.; Vermolen, F. J.; García-Aznar, J. M. A mathematical model for cell differentiation, as an evolutionary and regulated process. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2014. DOI: 10.1080/10255842.2012.736503
- Valero, C.; Javierre, E.; García-Aznar, J. M.; Gómez-Benito, M. J. Nonlinear finite element simulations of injuries with free boundaries: Application to surgical wounds. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING. 2014. DOI: 10.1002/cnm.2621
- Elosegui-Artola, A.; Jorge-Peñas, A.; Moreno-Arotzena, O.; Oregi, A.; Lasa, M.; García-Aznar, J.M.; de Juan-Pardo, E.M.; Aldabe, R. Image analysis for the quantitative comparison of stress fibers and focal adhesions. PLOS ONE. 2014. DOI: 10.1371/journal.pone.0107393
- Moreno-Arotzena, Oihana; Mendoza, Gracia; Cóndor, Mar; Rüberg, Thomas; García Aznar, José Manuel. Inducing chemotactic and haptotactic cues in microfluidic devices for three-dimensional in vitro assays. BIOMICROFLUIDICS. 2014. DOI: 10.1063/1.4903948
- Vahdati,A.; Walscharts,S.; Jonkers,I.; Garcia-Aznar,J.; Vander Sloten,J.; Van Lenthe,G. H. Role of subject-specific musculoskeletal loading on the prediction of bone density distribution in the proximal femur. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2014. DOI: 10.1016/j.jmbbm.2013.11.015
- Alierta, J. A.; Pérez, M. A.; García-Aznar, J. M. An interface finite element model can be used to predict healing outcome of bone fractures. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2014. DOI: 10.1016/j.jmbbm.2013.09.023
- Valero, Clara; Javierre, Etelvina; García-Aznar, José Manuel; Gómez-Benito, Maróa José. A cell-regulatory mechanism involving feedback between contraction and tissue formation guides wound healing progression. PLOS ONE. 2014. DOI: 10.1371/journal.pone.0092774
- Borau, Carlos; Polacheck, William J; Kamm, Roger D; García-Aznar, José Manuel. Probabilistic Voxel-Fe model for single cell motility in 3D. IN SILICO CELL AND TISSUE SCIENCE. 2014. DOI: 10.1186/2196-050X-1-2
- Escribano, J.; Sánchez, M.T.; García-Aznar, J.M. A discrete approach for modeling cell-matrix adhesions. COMPUTATIONAL PARTICLE MECHANICS. 2014. DOI: 10.1007/s40571-014-0006-7
- Borau, C.; Kamm, R.D.; García-Aznar, J.M. A time-dependent phenomenological model for cell mechano-sensing. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2014. DOI: 10.1007/s10237-013-0508-x
- Van Oosterwyck, H; Rodríguez, Jf; Doblaré, M; García-Aznar, Jm. An affine micro-sphere-based constitutive model, accounting for junctional sliding, can capture F-actin network mechanics. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2013. DOI: 10.1080/10255842.2011.648626
- Valero, C; Javierre, E; García Aznar, J.M.; Gómez Benito, M.J. Numerical modelling of the angiogenesis process in wound contraction. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2013. DOI: 10.1007/s10237-012-0403-x
- Acosta Santamaría,V. A.;García Aznar,J. M.;Ochoa,I.;Doblare,M. Effect of Sample Pre-Contact on the Experimental Evaluation of Cartilage Mechanical Properties. EXPERIMENTAL MECHANICS. 2013. DOI: 10.1007/s11340-012-9698-x
- Santamaría, V. A. A.; Malvè, M.; Duizabo, A.; Mena Tobar, A.; Gallego Ferrer, G.; García Aznar, J. M.; Doblaré, M.; Ochoa, I. . Computational methodology to determine fluid related parameters of non regular three-dimensional scaffolds. ANNALS OF BIOMEDICAL ENGINEERING. 2013. DOI: 10.1007/s10439-013-0849-8
- Palacio,J.;Jorge-Penas,A.;Munoz-Barrutia,A.;Ortiz-De-Solorzano,C.;de Juan-Pardo,E.;Garcia-Aznar,J. M. Numerical estimation of 3D mechanical forces exerted by cells on non-linear materials. JOURNAL OF BIOMECHANICS. 2013. DOI: 10.1016/j.jbiomech.2012.10.009
- Prokharau,P. A.;Vermolen,F. J.;Garcia-Aznar,J. M. Numerical method for the bone regeneration model, defined within the evolving 2D axisymmetric physical domain. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2013. DOI: 10.1016/j.cma.2012.09.017
- Izal, I.;Aranda, P.;Sanz-Ramos, P.;Ripalda, P.;Mora, G.;Granero-Moltó, F.;Deplaine, H.;Gómez-Ribelles, J. L.;Ferrer, G. G.;Acosta, V.;Ochoa, I.;García-Aznar, J. M.;Andreu, E. J.;Monleón-Pradas, M.;Doblaré, M.;Prósper, F. Culture of human bone marrow-derived mesenchymal stem cells on of poly(l-lactic acid) scaffolds: Potential application for the tissue engineering of cartilage. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY. 2013. DOI: 10.1007/s00167-012-2148-6
- Fernández,J. R.;García-Aznar,J. M.;Martínez,R. Piezoelectricity could predict sites of formation/resorption in bone remodelling and modelling. JOURNAL OF THEORETICAL BIOLOGY. 2012. DOI: 10.1016/j.jtbi.2011.09.032
- Rey,R.;Javierre,E.;García,S. J.;Der Zwaag,S. V.;García-Aznar,J. M. Numerical study of the scratch-closing behavior of coatings containing an expansive layer. SURFACE & COATINGS TECHNOLOGY. 2012. DOI: 10.1016/j.surfcoat.2011.09.069
- Prokharau,P. A.;Vermolen,F. J.;García-Aznar,J. M. Model for direct bone apposition on pre-existing surfaces, during peri-implant osseointegration. JOURNAL OF THEORETICAL BIOLOGY. 2012. DOI: 10.1016/j.jtbi.2012.03.025
- Acosta Santamaría, V. ;Deplaine, H.;Mariggió, D.;Villanueva-Molines, A.;García-Aznar, J. M.;Gómez Ribelles, J. L. ;Doblaré, M.;Gallego Ferrer, G.;Ochoa, I. Influence of the macro and micro-porous structure on the mechanical behavior of poly(l-lactic acid) scaffolds. JOURNAL OF NON-CRYSTALLINE SOLIDS. 2012. DOI: 10.1016/j.jnoncrysol.2012.08.001
- Borau, C.;Kim, T.;Bidone, T.;García-Aznar, J. M.;Kamm, R. D. Dynamic Mechanisms of Cell Rigidity Sensing: Insights from a Computational Model of Actomyosin Networks. PLOS ONE. 2012. DOI: 10.1371/journal.pone.0049174
- Reina-Romo, E.;Gómez-Benito, M. J.;Domínguez, J.;García-Aznar, J. M. A lattice-based approach to model distraction osteogenesis. JOURNAL OF BIOMECHANICS. 2012. DOI: 10.1016/j.jbiomech.2012.09.004
- Fernández,J. R.;García-Aznar,J. M.;Martínez,R. Numerical analysis of a piezoelectric bone remodelling problem. EUROPEAN JOURNAL OF APPLIED MATHEMATICS. 2012. DOI: 10.1017/S0956792512000150
- Reina-Romo, E.;Gómez-Benito, M. J.;Sampietro-Fuentes, A.;Domínguez, J. ;García-Aznar, J. M. Three-dimensional simulation of mandibular distraction osteogenesis: Mechanobiological analysis. ANNALS OF BIOMEDICAL ENGINEERING. 2011
- González-Torres, L. A.;Gómez-Benito, M. J. ;García-Aznar, J. M. Evaluation of residual stresses due to bone callus growth: A computational study. JOURNAL OF BIOMECHANICS. 2011. DOI: 10.1016/j.jbiomech.2011.04.021
- Ojeda, Joaquin; Martínez-Reina, Javier; García-Aznar, José Manuel; Domínguez, Jaime; Doblaré, M. Numerical simulation of bone remodelling around dental implants. PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE. 2011. DOI: 10.1177/0954411911410165
- Gómez-Benito,M. J.;González-Torres,L. A.;Reina-Romo,E.;Grasa,J.;Seral,B.;García-Aznar,J. M. Influence of high-frequency cyclical stimulation on the bone fracture-healing process: Mathematical and experimental models. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A: MATHEMATICAL, PHYSICAL AND ENGINEERING SCIENCES. 2011. DOI: 10.1098/rsta.2011.0153
- Martínez-Reina, J.; Domínguez, J.; García-Aznar, J. M. Effect of porosity and mineral content on the elastic constants of cortical bone: A multiscale approach. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2011. DOI: 10.1007/s10237-010-0236-4
- Borau, C.;Kamm, R. D.;García-Aznar, J. M. Mechano-sensing and cell migration: A 3D model approach. PHYSICAL BIOLOGY. 2011. DOI: 10.1088/1478-3975/8/6/066008
- Fernández, J. R.;García-Aznar, J. M.;Martínez, R. ;Viaño, J. M. Numerical analysis of a strain-adaptive bone remodelling problem. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2010
- Grasa, J.; Gomez-Benito, M.J.; Gonzalez-Torres, L.A.; Asiain, D.; Quero, F.; Garcia-Aznar, J.M. Monitoring In Vivo Load Transmission Through an External Fixator. ANNALS OF BIOMEDICAL ENGINEERING. 2010. DOI: 10.1007/s10439-009-9889-5
- Pérez, M. A.;Fornells, P.;Doblaré, M. ;García-Aznar, J. M. Comparative analysis of bone remodelling models with respect to computerised tomography-based finite element models of bone. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2010
- Reina-Romo, E.;Sampietro-Fuentes, A.;Gomez-Benito, M. J.;Dominguez, J.;Doblare, M. ;Garcia-Aznar, J. M. Biomechanical response of a mandible in a patient affected with hemifacial microsomia before and after distraction osteogenesis. MEDICAL ENGINEERING & PHYSICS. 2010
- Reina-Romo Esther; Gomez-Benito Maria Jose; Garcia-Aznar Jose Manuel; Dominguez J.; Doblare Castellano Manuel. Growth mixture model of distraction osteogenesis: effect of pre-traction stresses. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2010. DOI: 10.1007/s10237-009-0162-5
- Sanz-Herrera José Antonio; Doblare Castellano Manuel; Garcia-Aznar José Manuel. Scaffold microarchitecture determines internal bone directional growth structure: A numerical study. JOURNAL OF BIOMECHANICS. 2010. DOI: 10.1016/j.jbiomech.2010.05.027
- Gonzalez-Torres Libardo; Gomez-Benito María José; Doblare Castellano Manuel; Garcia-Aznar José Manuel. Influence of the frequency of the external mechanical stimulus on bone healing: A computational study. MEDICAL ENGINEERING & PHYSICS. 2010. DOI: 10.1016/j.medengphy.2010.01.010
- Moreo Pedro;Gaffney E. A.; Garcia-Aznar José Manuel; Doblare Castellano Manuel. On the Modelling of Biological Patterns with Mechanochemical Models: Insights from Analysis and Computation. BULLETIN OF MATHEMATICAL BIOLOGY. 2010. DOI: 10.1007/s11538-009-9452-4
- Perez Anson María Angeles; Fornells Pere; Doblare Castellano Manuel; Garcia-Aznar José Manuel. Comparative analysis of bone remodelling models with respect to computerised tomography-based finite element models of bone. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2010. DOI: 10.1080/10255840903045029
- Reina-Romo Esther; Gomez-Benito María José; Garcia-Aznar José Manuel; Dominguez J; Doblare Castellano Manuel. An interspecies computational study on limb lengthening. PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE. 2010. DOI: 10.1243/09544119JEIM787
- Javierre, E.;Moreo,P.;Doblare,M.;Garcia-Aznar,J. Numerical Modeling of a Mechano-Chemical Theory for Wound Contraction Analysis. INTERNATIONAL JOURNAL OF SOLIDS AND STRUCTURES. 2009
- Perez, M. A.;Nuno,N.;Madrala,A.;Garcia-Aznar,J. M.;Doblare,M. Computational Modelling of Bone Cement Polymerization: Temperature and Residual Stresses. COMPUTERS IN BIOLOGY AND MEDICINE. 2009. DOI: 10.1016/j.compbiomed.2009.06.002
- Roker, S.;Diederichs, S.;Stark, Y.;Bohm, S.;Ochoa, I.;Sanz, J. A.;Garcia-Aznar, J.;Doblare, M.;Van Griensven, M.;Scheper, T.;Kasper, C. Novel 3D Biomaterials for Tissue Engineering Based on Collagen and Macroporous Ceramics. MATERIALWISSENSCHAFT UND WERKSTOFFTECHNIK. 2009
- Sanz-Herrera, J.;Moreo,P.;Garcia-Aznar,J.;Doblare,M. On the Effect of Substrate Curvature on Cell Mechanics. BIOMATERIALS. 2009
- Martinez-Reina, J.;Garcia-Aznar,J. M.;Dominguez,J.;Doblare,M. A Bone Remodelling Model Including the Directional Activity of BMUs. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2009
- Garcia-Aznar, J. M.;Bayod,J.;Rosas,A.;Larrainzar,R.;Garcia-Bogalo,R.;Doblare,M.;Llanos,L. F. Load Transfer Mechanism for Different Metatarsal Geometries: A Finite Element Study. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME. 2009
- Garzon-Alvarado, D. A.;Garcia-Aznar,J. M.;Doblare,M. A Reaction-Diffusion Model for Long Bones Growth. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2009
- Moreo Calvo Pedro; Garcia-Aznar José Manuel; Doblare Castellano Manuel. Bone ingrowth on the surface of endosseous implants. Part 1: Mathematical model. JOURNAL OF THEORETICAL BIOLOGY. 2009. DOI: 10.1016/j.jtbi.2008.07.040
- Garzon-Alvarado Diego; Garcia-Aznar Jose Manuel; Doblare Castellano Manuel. Appearance and location of secondary ossification centres may be explained by a reaction-diffusion mechanism. COMPUTERS IN BIOLOGY AND MEDICINE. 2009. DOI: 10.1016/j.compbiomed.2009.03.012
- Ochoa Garrido Ignacio; Sanz-Herrera Jose Antonio; Garcia-Aznar Jose Manuel; Doblare Castellano Manuel; Yunos Darmawati Mohamad; Boccaccini Aldo R. Permeability evaluation of 45S5 Bioglass (R)-based scaffolds for bone tissue engineering. JOURNAL OF BIOMECHANICS. 2009. DOI: 10.1016/j.jbiomech.2008.10.030
- Sanz-Herrera, J. A.;Garcia-Aznar,J. M.;Doblare,M. A Mathematical Approach to Bone Tissue Engineering. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A: MATHEMATICAL, PHYSICAL AND ENGINEERING SCIENCES. 2009
- Sanz-Herrera, J. A.;Garcia-Aznar,J. M.;Doblare,M. On Scaffold Designing for Bone Regeneration: A Computational Multiscale Approach. ACTA BIOMATERIALIA. 2009
- Ochoa, I.;Sanz-Herrera,J. M.;Doblare,M.;Garcia-Aznar,J. M. Simulation in Silico of Bone Tissue Regeneration within Polimeric Scaffolds. TISSUE ENGINEERING. PART A. 2009
- Perez, M. A.;Garcia-Aznar,J. M.;Doblare,M. Does Increased Bone-Cement Interface Strength have Negative Consequences for Bulk Cement Integrity? A Finite Element Study. ANNALS OF BIOMEDICAL ENGINEERING. 2009. DOI: 10.1007/s10439-008-9616-7
- Reina-Romo, E.;Gomez-Benito,M.;Garcia-Aznar,J. M.;Domínguez Hernández, Javier;Doblare, M. Modeling Distraction Osteogenesis: Analysis of the Distraction Rate. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2009
- Roeker, S.;Diederichs, S.;Stark, Y.;Boehm, S.;Ochoa, I.;Sanz, J. A.;Garcia-Aznar, J. M.;Doblare, M.;Van Griensven, M.;Scheper, T.;Kasper, C. Novel Collagen and Ceramic Based 3D Biomaterials for Tissue Engineering Applications. TISSUE ENGINEERING. PART A. 2008
- Sanz-Herrera, J.;Garcia-Aznar,J.;Doblare,M. Micro-Macro Numerical Modelling of Bone Regeneration in Tissue Engineering. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2008
- Sanz-Herrera, J.;Garcia-Aznar,J.;Doblare,M. Simulation of Bone Remodelling and Bone Ingrowth within Scaffolds. KEY ENGINEERING MATERIALS. 2008
- Perez, M. A.;Moreo,P.;Garcia-Aznar,J. M.;Doblare,M. Computational Simulation of Dental Implant Osseointegration through Resonance Frequency Analysis. JOURNAL OF BIOMECHANICS. 2008. DOI: 10.1016/j.jbiomech.2007.09.013
- Martinez-Reina, J.;Garcia-Aznar,J. M.;Dominguez,J.;Doblare,M. On the Role of Bone Damage in Calcium Homeostasis. JOURNAL OF THEORETICAL BIOLOGY. 2008
- Alexander Garzon, D.;Garcia, ,J. Manuel;Doblare, M. Computer Simulation of Long Bone Development: A Model of Endochondral Ossification. REVISTA FACULTAD DE INGENIERIA-UNIVERSIDAD DE ANTIOQUIA. 2008
- Sanz-Herrera Jose Antonio; Kasper Cornelia, Van Griensven Martijn; Garcia-Aznar Jose Manuel; Ochoa Garrido Ignacio; Doblare Castellano Manuel. Mechanical and flow characterization of Sponceram (R) carriers: Evaluation by homogenization theory and experimental validation. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH - PART B APPLIED BIOMATERIALS. 2008. DOI: 10.1002/jbm.b.31065
- Moreo, P.;Garcia-Aznar,J. M.;Doblare,M. Modeling Mechanosensing and its Effect on the Migration and Proliferation of Adherent Cells. ACTA BIOMATERIALIA. 2008
- Sanz-Herrera, J.;Garcia-Aznar,J.;Doblare,M. A Mathematical Model for Bone Tissue Regeneration Inside a Specific Type of Scaffold. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2008
- Reina, J. M.;Garcia-Aznar,J. M.;Dominguez,J.;Doblare,M. Numerical Estimation of Bone Density and Elastic Constants Distribution in a Human Mandible. JOURNAL OF BIOMECHANICS. 2007
- Moreo, P.;Perez,M. A.;Garcia-Aznar,J.;Doblare,M. Modelling the Mechanical Behaviour of Living Bony Interfaces. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2007. DOI: 10.1016/j.cma.2007.03.020
- Brigido Diego, R.;Más Esteiles,J.;Sanz,J. A.;Garcia-Aznar,J.;Salmerón Sanchez,M. Polymer Scaffolds with Interconnected Spherical Pores and Controlled Architecture for Tissue Engineering: Fabrication, Mechanical Properties, and Finite Element Modeling. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH - PART B APPLIED BIOMATERIALS. 2007
- Fornells, P.;Garcia-Aznar,J. M.;Doblare,M. A Finite Element Dual Porosity Approach to Model Deformation-Induced Fluid Flow in Cortical Bone. ANNALS OF BIOMEDICAL ENGINEERING. 2007
- Garcia-Aznar, J. M.;Kuiper,J. H.;Gomez-Benito,M. J.;Doblare,M.;Richardson,J. B. Computational Simulation of Fracture Healing: Influence of Interfragmentary Movement on the Callus Growth. JOURNAL OF BIOMECHANICS. 2007
- Gomez-Benito, M. J.; Moreo,P.; Perez,M. A.; Paseta,O.; Garcia-Aznar,J. M.; Barrios,C.; Doblare,M. A Damage Model for the Growth Plate: Application to the Prediction of Slipped Capital Epiphysis. JOURNAL OF BIOMECHANICS. 2007. DOI: 10.1016/j.jbiomech.2007.04.018
- Gomez-Benito, M. J.;Fornells,P.;Garcia-Aznar,J. M.;Seral,B.;Seral-Innigo,F.;Doblare,M. Computational Comparison of Reamed Versus Unreamed Intramedullary Tibial Nails. JOURNAL OF ORTHOPAEDIC RESEARCH. 2007
- Moreo, P.;Garcia-Aznar,J. M.;Doblare,M. A Coupled Viscoplastic Rate-Dependent Damage Model for the Simulation of Fatigue Failure of Cement-Bone Interfaces. INTERNATIONAL JOURNAL OF PLASTICITY. 2007
- Moreo, P.;Garcia-Aznar,J. M.;Doblare,M. Computational Simulation of Cell Migration Under Different Substrate Stiffness. TISSUE ENGINEERING. 2007
- Sanz, J. A.;Garcia-Aznar,J. M.;Doblare,M. Micro-Macro Coupling Approach of Bone Growth within Non-Reabsorbable Scaffolds. TISSUE ENGINEERING. 2007
- Sanz-Herrera, J. A.;Kasper, C.;Van Griensven, M.;Garcia-Aznar, J. M.;Aznar, J. M.;Ochoa, I.;Doblare, M. Experimental and Computational Characterization of Sponceram Supports. TISSUE ENGINEERING. 2007
- Moreo,P.; Perez,M. A.; Garcia-Aznar,J. M.; Doblare,M. Modelling the mixed-mode failure of cement-bone interfaces. ENGINEERING FRACTURE MECHANICS. 2006. DOI: 10.1016/j.engfracmech.2006.01.005
- Seral-Garcia,B.;Perez-Anson,M. A.;Seral-Inigo,F.;Garcia-Aznar,J. M.;Doblare-Castellano,M. MODELO DE INTERFAZ CEMENTO-VASTAGO EN ARTROPLASTIAS TOTALES DE CADERA. ESTUDIO DE LA SUPERFICIE CON ELEMENTOS FINITOS. REVISTA DE ORTOPEDIA Y TRAUMATOLOGÍA. 2006
- Perez, M. A.;Grasa, J.;Garcia Aznar, J. M.;Bea, J. A.;Doblare, M. Probabilistic analysis of the influence of the bonding degree of the stem-cement interface in the performance of cemented hip prostheses. JOURNAL OF BIOMECHANICS. 2006. DOI: 10.1016/j.jbiomech.2005.05.025
- Perez, M.A.; Garcia-Aznar, J.M.; Doblare, M.; Seral, B.; Seral, F. A comparative FEA of the debonding process in different concepts of cemented hip implants. MEDICAL ENGINEERING & PHYSICS. 2006. DOI: 10.1016/j.medengphy.2005.09.007
- Pérez,María Angeles;García-Aznar,José Manuel;Doblaré,Manuel. Simulación del deterioro del cemento y sus interfaces en prótesis de cadera. REVISTA INTERNACIONAL DE METODOS NUMERICOS PARA CALCULO Y DISENO EN INGENIERIA. 2006
- Martinez,G.;Aznar,J. M. G.;Doblare,M.;Cerrolaza,M. External bone remodeling through boundary elements and damage mechanics. MATHEMATICS AND COMPUTERS IN SIMULATION. 2006
- Gomez-Benito,M. J.;Garcia-Aznar,J. M.;Kuiper,J. H.;Doblare,M. A 3D computational simulation of fracture callus formation: Influence of the stiffness of the external fixator. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME. 2006
- Seral, B; García-Aznar, J. M.; Doblaré, M.; Pérez, M. A.; Seral, F. Periprosthetic bone remodelling. A finite element study of the influence of the implant design. JOURNAL OF APPLIED BIOMATERIALS & BIOMECHANICS. 2005
- Gomez Benito, M. J.;Garcia Aznar, J. M.;Kuiper, J. H.;Doblare, M. Influence of Fracture Gap Size on the Pattern of Long Bone Healing: a Computational Study. JOURNAL OF THEORETICAL BIOLOGY. 2005
- Garcia Aznar, J. M.;Rueberg, T.;Doblare, M. A Bone Remodelling Model Coupling Microdamage Growth and Repair by 3d Bmu-Activity. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. 2005
- Doblare, M.;Cueto, E.;Calvo, B.;Martinez, M.A.;Garcia, J.M.;Cegoñino, J. On the employ of meshless methods in biomechanics. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. 2005
- Perez, M.A.;Garcia, J.M.;Doblare, M. Analysis of the debonding of the stem-cement interface in intramedullary fixation using a non-linear fracture mechanics approach. ENGINEERING FRACTURE MECHANICS. 2005. DOI: 10.1016/j.engfracmech.2004.09.002
- Gomez Benito, M. J.;Garcia Aznar, J. M.;Doblare, M. Finite Element Prediction of Proximal Femoral Fracture Patterns Under Different Loads. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME. 2005
- Grasa, J.;Perez, M. A.;Bea, J. A.;Garcia Aznar, J. M.;Doblare, M. A Probabilistic Damage Model for Acrylic Cements. Application to the Life Prediction of Cemented Hip Implants. INTERNATIONAL JOURNAL OF FATIGUE. 2005. DOI: 10.1016/j.ijfatigue.2004.12.009
- Seral, B.;Garcia, J. M.;Cegonino, J.;Doblare, M.;Seral, F. Finite Element Study of Intramedullary Osteosynthesis in the Treatment of Trochanteric Fractures of the Hip: Gamma and Pfn. INJURY. 2004
- Ramtani, S.;Garcia, J. M.;Doblare, M. Computer Simulation of an Adaptive Damage-Bone Remodeling Law Applied to Three Unit-Bone Bars Structure. COMPUTERS IN BIOLOGY AND MEDICINE. 2004
- Doblare, M.;Garcia, J. M.;Gomez, M. J. Modelling Bone Tissue Fracture and Healing: a Review. ENGINEERING FRACTURE MECHANICS. 2004
- Cegoñino, J. ;Garcia Aznar, J. M. ;Doblare, M. ;Palanca, D. ;Seral, B. ;Seral, F. A comparative analysis of different treatments for distal femur fractures using the finite element method. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2004
- Doblare, M. ;Garcia, J. M. On the modelling bone tissue fracture and healing of the bone tissue. ACTA CIENTÍFICA VENEZOLANA. 2003
- Doblare, M.;Garcia, J.M.;Cegonino, J. Development of an internal bone remodelling theory and applications to some problems in orthopaedic biomechanics. MECCANICA. 2002
- Garcia, J.M.;Doblare, M.;Cegonino, J. Bone remodelling simulation: A tool for implant design. COMPUTATIONAL MATERIALS SCIENCE. 2002
- Doblare, M. ;Garcia, J. M. Anisotropic bone remodelling model based on a continuum damage-repair theory. JOURNAL OF BIOMECHANICS. 2002
- Seral, B. ;Garcia, J. M. ;Cegonino, J. ;Doblare, M. ;Palanca, D. ;Seral, F. Extramedullary vs. intramedullary osteosynthesis in trochanteric hip fractures. Three-dimensional finite-element analysis OSTEOSINTESIS EXTRAMEDULAR VS. INTRAMEDULAR EN LAS FRACTURAS TROCANTEREAS DE CADERA. ANALISIS 3D CON ELEMENTOS FINITOS. REVISTA DE ORTOPEDIA Y TRAUMATOLOGÍA. 2001
- Garcia, J. M;Martinez, M. A;Doblare, M. An anisotropic internal-external bone adaptation model based on a combination of CAO and continuum damage mechanics technologies. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING. 2001
- Doblare, M. ;Garcia, J. M. Application of an anisotropic bone-remodelling model based on a damage-repair theory to the analysis of the proximal femur before and after total hip replacement. JOURNAL OF BIOMECHANICS. 2001
- Garcia, J. M;Doblare, M. ;Seral, B. ;Seral, F. ;Palanca, D. ;Gracia, L. Three-dimensional finite element analysis of several internal and external pelvis fixations. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME. 2000
- García, Jm; Doblaré, M; Gracia, L. Simulación numérica del problema de remodelación ósea 3-D para huesos largos. ANALES DE INGENIERÍA MECÁNICA. 1998
Comunicaciones
- Borau, Carlos; Amo, Cristina Del; Asín, Jesús; Movilla, Nieves; Cóndor, Mar; García-Aznar, José Manuel. A workbench for biomedical applications based on image analysis. LECTURE NOTES IN COMPUTATIONAL VISION AND BIOMECHANICS. 2018. DOI: 10.1007/978-3-319-68195-5_59
- del Amo, C.; Borau, C.; Asín, J.; García-Aznar, J. M. Quantification of sprouting angiogenesis under the effect of different growth factors involved in the tumor microenvironmen. CANCER IMMUNOLOGY RESEARCH. 2017. DOI: 10.1158/2326-6074.TUMIMM16-B85
- Pérez Ansón, María de los Ángeles; García-Aznar, José Manuel; Doblaré, Manuel. Modelling the bone-cement interface in cemented hip implants. JOURNAL OF BIOMECHANICS. 2008. DOI: 10.1016/S0021-9290(08)70068-X
Capítulos
- Mechanobiological modelling of angiogenesis: impact on tissue engineering and bone regeneration. E. Reina-Romo, C. Valero, C. Borau, R. Rey, E. Javierre, M.J. Gómez-Benito, J. Domínguez, J.M. García-Aznar. COMPUTATIONAL MODELLING IN TISSUE ENGINEERING. 2013
- In-Silico Models as a Tool for the Design of Specific Treatments: Applications in Bone Regeneration. E. Reina-Romo, M. J. Gómez-Benito, L. A. González-Torres, J. Domínguez, J. M. García-Aznar. TECHNOLOGIES FOR MEDICAL SCIENCES. 2012
- In silico models as a tool for the design of medical device technologies. J. M. García-Aznar, M.A. Pérez, M.J. Gómez-Benito, J.A. Sanz-Herrera, E. Reina-Romo. TECHNOLOGY AND MEDICAL SCIENCES. 2011
- Mechanobiological models for Bone Tissue. Applications to Implant Design. Gomez-Benito Maria Jose; Perez Anson Maria Angeles; Doblare Castellano Manuel. BIOMECHANICS OF HARD TISSUES. 2010
- A Mechanobiological Formulation of Bone Healing. M. Doblaré; J.M. García-Aznar; M.J. Gómez-Benito. MECHANICS OF BIOLOGICAL TISSUE. 2006
Colaboraciones en ediciones de revista
- CMES - Computer Modeling in Engineering and Sciences. 1526-1492. 01/06/19
- PLoS ONE. 1932-6203. 03/03/14
- Computational Particle Mechanics. 2196-4378. 28/06/13
- In Silico Cell and Tissue Science. 2196-050X. 09/03/13
- BONE. 8756-3282. 23/02/11
Proyectos
- VASTO / VAScularised Tumour Organoids on a chip with human placenta vessels as a preclinical model for anticancer
therapies. 01/11/23 - 30/04/25
- METASTRA / COMPUTER-AIDED EFFECTIVE FRACTURE RISK STRATIFICATION OF PATIENTS WITH VERTEBRAL METASTASES (nº GA: 101080135)
FOR PERSONALISED TREATMENT THROUGH ROBUST COMPUTATIONAL MODELS VALIDATED IN CLINICAL
SETTINGS. 01/07/23 - 30/06/28
- T50_23R: Multiescala en Ingeniería Mecánica y Biológica (M2BE). 01/01/23 - 31/12/25
- PID2021-122409OB-C21: Predictive modeling and simulation of patient-derived tumor organoids: unraveling the role of matrix stiffness and glucose metabolism on tumor growth. (TUMATRIX-MODELING). 01/09/22 - 31/08/25
- ICoMICS / Individual and Collective Migration of the Immune Cellular System (GA H2020 ERC 101018587). 01/01/22 - 31/12/26
- LMP29_21: CART-TEST: Testeo in-vitro de la funcionalidad de inmunoterapias para tumores sólidos. 18/09/21 - 30/09/23
- T50_20R: Multiscale In Mechanical And Biological Engineering (M2BE). 01/01/20 - 31/12/22
- PRX18/00147: MODELADO Y SIMULACIÓN DE LA FORMACIÓN Y LA MIGRACIÓN DE ESFEROIDES TUMORALES EN DIFERENTES CONDICIONES MECANO-QUIMICAS. ESTANCIA EN UNIVERSITY OF OXFORD (REINO UNIDO). 01/06/19 - 31/08/19
- LMP74_18: CELLBIOPRINT: IMPRESIÓN Y CARACTERIZACIÓN DE ANDAMIOS BIOCOMPATIBLES. 01/03/19 - 30/11/20
- RTI2018-094494-B-C21: MICROFLUÍDICA, MECANOBIOLOGÍA Y ANÁLISIS DE IMAGEN PARA LA SIMULACIÓN DEL CRECIMIENTO TUMORAL EN 3D. 01/01/19 - 30/09/22
- PRIMAGE / PRedictive In-silico Multiscale Analytics to support cancer personalized diaGnosis and prognosis, empowered by imaging biomarkers (H2020 G.A. no. 826494). 01/12/18 - 31/05/23
- BFU2017-90692-REDT: RED DE EXCELENCIA EN MECANOBIOLOGÍA. 01/07/18 - 31/12/20
- VPH CONFERENCE 2018: VPH FORM IN SILICO MEDICINE. 22/09/17 - 21/09/18
- CADENCE / Catalytic Dual-Function Devices Against Cancer (H2020 nº GA 742684). 01/09/17 - 31/08/23
- IMAGO / Image Analysis Online Services for in-vitro experiments (G.A. no. 737543). 01/09/17 - 28/02/19
- CURABONE / Predictive models and simulations in bone regeneration: a multiscale patient-specific approach (G.A. no. 722535). 01/04/17 - 31/03/21
- GRUPO DE REFERENCIA MULTISCALE IN MECHANICAL AND BIOLOGICAL ENGINEERING (M2BE). 01/01/17 - 31/12/19
- DPI2015-64221-C2-1-R: DISEÑO Y FABRICACIÓN DE DISPOSITIVOS MICROFLUÍDICOS PARA EL ESTUDIO MEDIANTE ANÁLISIS DE IMAGEN Y MODELOS NUMÉRICOS DE LA MECÁNICA DE LA EXTRAVASACIÓN TUMORAL. 01/01/16 - 30/06/19
- EQ/12/16: REPARACIÓN DE UNA CÁMARA DE INCUBACIÓN INTEGRADA EN MICROSCOPIO NIKON. 01/01/16 - 31/12/16
- GRUPO CONSOLIDADO T86 M2BE- MULTISCALE IN MECHANICAL AND BIOLOGICAL ENGINEERING. 01/01/16 - 31/12/16
- REPARACIÓN DE UN AUTOCLAVE PARA ESTERILIZACIÓN DE SÓLIDOS Y LÍQUIDOS. Marca TUTTNAUER, Mod. 3870 ELV. 01/01/16 - 30/11/16
- GRUPO CONSOLIDADO T86 M2BE- MULTISCALE IN MECHANICAL AND BIOLOGICAL ENGINEERING. 01/01/15 - 31/12/15
- REPARACIÓN DE UNA CABINA BIO-II-A DE CULTIVO CELULAR DE TELSTAR. 01/01/15 - 31/12/15
- GRUPO CONSOLIDADO T86 M2BE. MULTIESCALA EN INGENIERÍA MECÁNICA Y BIOLÓGICA (M2BE). 01/01/14 - 31/12/14
- REPARACIÓN DE:
UNA CENTRAL DE GASES Y LÍNEA DE CO2 Y N2 PARA INCUBADORES DE CULTIVO CELULAR.1208,94. 01/01/14 - 31/12/14
- ANULADO POR RENUNCIA
PRX12/00026 MODELADO MATEMÁTICO DE LA MIGRACIÓN CELULAR EN 3D.
ESTANCIA EN EL CENTRE FOR MATHEMATICAL BIOLOGY (UNIVERSITY OF OXFORD). 01/06/13 - 31/08/13
- DPI2012-38090-C03-01 MODELADO MULTIESCALA PARA LA SIMULACIÓN PREDICTIVA DE LA MIGRACIÓN CELULAR EN 3D: EL PAPEL DE LA INTERACCIÓN CÉLULA-MATRIZ. 01/01/13 - 31/12/15
- GRUPO CONSOLIDADO T86 MULTIESCALA EN INGENIERÍA MECÁNICA Y BIOLÓGICA (M2BE). 01/01/13 - 31/12/13
- INSILICO-CELL/Predictive modelling and simulation in mechano-chemo-biology: a computer multi-approach. 01/11/12 - 31/05/18
- CADBONE / PATIENT-SPECIFIC PREDICTIONS FOR BONE TREATMENTS. 01/01/12 - 31/12/15
- V.I. EXCELENCIA 2011.ESTANCIA MOHAMMAD R.K MOFRAD DE LA UNIVERSIDAD DE CALIFORNIA EN BERKELEY (EE.UU.). 01/01/12 - 31/12/12
- GRUPO CONSOLIDADO T86 MULTIESCALA EN INGENIERIA MECANICA Y BIOLOGICA (M2BE). 01/01/11 - 31/12/12
- DPI2009-14115-C03-01. MODELADO DEL EFECTO DE LA MECÁNICA CELULAR EN LA MIGRACIÓN CELULAR. 01/01/10 - 31/12/12
- PT2009-0028: SIMULACIÓN NUMÉRICA DE LA REGENERACIÓN ÓSEA: MODELOS MATEMÁTICOS DE OPTIMIZACIÓN. 01/01/10 - 30/09/12
- PI031/08. INGENIERIA DE TEJIDOS PARA LA REGENERACIÓN DEL CARTILAGO ARTICULAR: INFLUENCIA DE FACTORES MECANICOS. 01/10/08 - 30/09/10
- CTPP05/2007 TERAPIA CELULAR PROANGIOGÉNICA EN ENFERMEDAD ISQUÉMICA. 01/01/08 - 31/12/09
- GRUPO EXCELENTE T32 "GEMM" GRUPO DE MECANICA ESTRUCTURAL Y MODELADO DE MATERIALES. 01/01/08 - 31/12/10
- DPI2006-09692. DISEÑO DE UN FIJADOR EXTERNO "INTELIGENTE" PARA LA CONSOLIDACIÓN DE FRACTURAS DE HUESOS LARGOS. 01/10/06 - 30/09/09
- CONVENIO CON IBERCAJA PARA LA REALIZACIÓN DEL PROYECTO "MECANOBIOLOGIA DE LA REGENERACION TISULAR. MODELADO Y VALIDACION IN-VITRO". 12/06/06 - 31/12/07
- DECISSION SUPPORT SOFTWARE FOR ORTHOPAEDIC SURGERY "DESSOS". 01/01/06 - 31/12/08
- DESSOS-CONTRACT Nº027252. DECISION SUPPORT SOFTWARE FOR ORTHOPAEDIC SURGERY. 01/01/06 - 30/09/09
- PI052006. IMAGEN MEDICA MOLECULAR Y MULTIMODALIDAD (IM3): SIMULACION DEL SISTEMA CARDIOVASCULAR. 31/12/05 - 30/12/06
- INF2005-TEC-011. MICROMANIPULADOR PARA ELECTROFISIOLOGIA CON CONTROL DINAMICO PATACHMAN NP2 Y UN FERMENTADOR BIOREACTOR NBS MODELO BIOFLO 110. 13/07/05 - 31/12/05
- GRUPO EXCELENTE T32 GRUPO DE MECANICA ESTRUCTURAL Y MODELADO DE MATERIALES (GEMM). 01/01/05 - 31/12/07
- NUEVAS TECNOLOGIAS 2004.DESARROLLO DEL ADD DE APOYO A LA DOCENCIA DE LA ASIGNATURA ESTRUCTURAS DE HORMIGON ARMADO Y PRETENSADO. 07/05/04 - 31/12/04
- P008/2001.SIMULACION BIOMECANICA DEL PROCESO DE REPARACION DE FRACTURAS OSEAS. 01/01/02 - 31/12/04
- DPI2000-1269-CO2-01. DISEÑO Y FABRICACION DE PROTOTIPOS DE PROTESIS PERSONALIZADAS PARA LA ARTICULACION TEMPORO-MANDIBULAR MEDIANTE TECNICAS. 28/12/00 - 27/12/03
- P-79/96.SISTEMA INTEGRAL PARA EL DISEÑO DE IMPLANTES OSEOS PERSONALIZADOS CON APLICACIONES AL APARATO LOCOMOTOR. 01/01/97 - 31/12/99
Modelos de utilidad
- U201932084. Dispositivo de encapsulado apto para aplicaciones microfluídicas. GARCÍA AZNAR, JOSÉ MANUEL - BLANCO MONEO, ALEJANDRO - AMO MATEOS, CRISTINA DEL - SANTOLARIA MAZO, JORGE. 2019
Patentes de invención
- P200930129. EQUIPO PARA MEDICIÓN DE LA PERMEABILIDAD DE ANDAMIAJES Y TEJIDOS CON DEFORMACIÓN MEDIANTE PERFUSIÓN. BEA CASCAROSA, JOSÉ ANTONIO - GARCÍA AZNAR, JOSÉ MANUEL - MARZO MAINAR, JOSÉ CARLOS - OCHOA GARRIDO, IGNACIO - SANZ HERRERA, JOSE ANTONIO - ACOSTA SANTAMARIA, VICTOR ANDRES - DOBLARÉ CASTELLANO, MANUEL. 2009
Spin off
Comités
- VicePresidente. European Society of Biomechanics. 08/07/08 - 01/07/12
UNIZAR teaching of the last six courses
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