Perfil (CV) del personal docente investigador

Lorente Cebrián, Silvia
Departamento: Departamento de Farmacología, Fisiología y Medicina Legal y Forense
Área: Fisiología
Centro: Facultad de Ciencias de la Salud y del Deporte

Research Institute: INSTITUTO AGROALIMENTARIO DE ARAGÓN (IA2)
Categoría profesional: Prof. Titular Univ.

Cargos
  • Delegada Adjunta al Decano para los Objetivos de Desarrollo Sostenible (ODS) en la Facultad de Ciencias de la Salud y del Deporte.


 
         

Artículos

  • Díez-Sainz, Ester; Aranaz, Paula; Amri, Ez-Zoubir; Riezu-Boj, José I.; Lorente-Cebrián, Silvia; Milagro, Fermín I. Plant miR8126-3p and miR8126-5p decrease lipid accumulation through modulation of metabolic genes in a human hepatocyte model that mimics steatosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024. DOI: 10.3390/ijms25031721

  • Laiglesia, Laura M.; Escoté, Xavier; Sáinz, Neira; Felix-Soriano, Elisa; Santamaría, Eva; Collantes, María; Fernández-Galilea, Marta; Colón-Mesa, Ignacio; Martínez-Fernández, Leyre; Quesada-López, Tania; Quesada-Vázquez, Sergio; Rodríguez-Ortigosa, Carlos; Arbones-Mainar, José M.; Valverde, Ángela M.; Martínez, J Alfredo; Dalli, Jesmond; Herrero, Laura; Lorente-Cebrián, Silvia; Villarroya, Francesc; Moreno-Aliaga, María J. Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice. MOLECULAR METABOLISM. 2023. DOI: 10.1016/j.molmet.2023.101749

  • Lopez-Yus, Marta; Frendo-Cumbo, Scott; del Moral-Bergos, Raquel; Garcia-Sobreviela, Maria Pilar; Bernal-Monterde, Vanesa; Rydén, Mikael; Lorente-Cebrian, Silvia; Arbones-Mainar, Jose M. CRISPR/Cas9-mediated deletion of adipocyte genes associated with NAFLD alters adipocyte lipid handling and reduces steatosis in hepatocytes in vitro. AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2023. DOI: 10.1152/ajpcell.00291.2023

  • Díez-Sainz, Ester; Lorente-Cebrián, Silvia; Aranaz, Paula; Amri, Ez-Zoubir; Riezu-Boj, José I.; Milagro, Fermín I. miR482f and miR482c-5p from edible plant-derived foods inhibit the expression of pro-inflammatory genes in human THP-1 macrophages. FRONTIERS IN NUTRITION. 2023. DOI: 10.3389/fnut.2023.1287312

  • Lopez-Yus, Marta; Casamayor, Carmen; Soriano-Godes, Juan Jose; Borlan, Sofia; Gonzalez-Irazabal, Yolanda; Garcia-Sobreviela, Maria Pilar; Garcia-Rodriguez, Beatriz; del Moral-Bergos, Raquel; Calmarza, Pilar; Artigas, Jose Maria; Lorente-Cebrian, Silvia; Bernal-Monterde, Vanesa; Sanz-Paris, Alejandro; Arbones-Mainar, Jose M. Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity. CARDIOVASCULAR DIABETOLOGY. 2023. DOI: 10.1186/s12933-023-02075-0

  • López-Yus, Marta; López-Pérez, Rebeca; García-Sobreviela, María Pilar; del Moral-Bergos, Raquel; Lorente-Cebrián, Silvia; Arbones-Mainar, José M. Adiponectin overexpression in C2C12 myocytes increases lipid oxidation and myofiber transition. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2022. DOI: 10.1007/s13105-021-00836-7

  • Lopez-Yus, Marta; Lorente-Cebrian, Silvia; del Moral-Bergos, Raquel; Horndler, Carlos; Garcia-Sobreviela, Maria Pilar; Casamayor, Carmen; Sanz-Paris, Alejandro; Bernal-Monterde, Vanesa; Arbones-Mainar, Jose M. Identification of novel targets in adipose tissue involved in non-alcoholic fatty liver disease progression. FASEB JOURNAL. 2022. DOI: 10.1096/fj.202200118RR

  • Díez-Sainz, Ester; Milagro, Fermín I.; Riezu-Boj, José I.; Lorente-Cebrián, Silvia. Effects of gut microbiota–derived extracellular vesicles on obesity and diabetes and their potential modulation through diet. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2021. DOI: 10.1007/s13105-021-00837-6

  • Marsetti, P. Sofia; Milagro, Fermín I.; Zulet, M.A.; Martínez, J. Alfredo; Lorente-Cebrián, Silvia. Changes in miRNA expression with two weight-loss dietary strategies in a population with metabolic syndrome. NUTRITION. 2021. DOI: 10.1016/j.nut.2020.111085

  • Graham, Catherine A.M.; Pilic, Leta; King, Alexandra; Nixon, Jonathan E.; Pipe, Julie; Holton, Juliet; Tamba, Krisztina; Hearne, Gary; Pedlar, Charles R.; Lorente-Cebrián, Silvia; González Muniesa, Pedro; Mavrommatis, Yiannis. Genetic differences in fat taste sensitivity and dietary intake in a UK female cohort. FOOD QUALITY AND PREFERENCE. 2021. DOI: 10.1016/j.foodqual.2021.104202

  • Díez-Sainz, Ester; Lorente-Cebrián, Silvia; Aranaz, Paula; Riezu-Boj, José I.; Martínez, J. Alfredo; Milagro, Fermín I. Potential mechanisms linking food-derived micrornas, gut microbiota and intestinal barrier functions in the context of nutrition and human health. FRONTIERS IN NUTRITION. 2021. DOI: 10.3389/fnut.2021.586564

  • Félix-Soriano, Elisa; Martínez-Gayo, Alejandro; Cobo, María José; Pérez-Chávez, Adriana; Ibáñez-Santos, Javier; Palacios Samper, Natalia; Goikoetxea Galarza, Iñaki; Cuervo, Marta; García-Unciti, Marisol; González-Muniesa, Pedro; Lorente-Cebrián, Silvia; Moreno-Aliaga, María J. Effects of DHA-Rich n-3 Fatty Acid Supplementation and/or Resistance Training on Body Composition and Cardiometabolic Biomarkers in Overweight and Obese Post-Menopausal Women. NUTRIENTS. 2021. DOI: 10.3390/nu13072465

  • Graham, C.A.M.; Pedlar, C.R.; Hearne, G.; Lorente-Cebrián, S.; González-Muniesa, P.; Mavrommatis, Y. The Association of Parental Genetic, Lifestyle, and Social Determinants of Health with Offspring Overweight. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2020. DOI: 10.1159/000505749

  • López-Pascual, A.; Lorente-Cebrián, S.; Moreno-Aliaga, M.J.; Martínez, J.A.; González-Muniesa, P. Inflammation stimulates hypoxia-inducible factor-1a regulatory activity in 3T3-L1 adipocytes with conditioned medium from lipopolysaccharide-activated RAW 264.7 macrophages. JOURNAL OF CELLULAR PHYSIOLOGY. 2019. DOI: 10.1002/jcp.26763

  • Lorente-Cebrián, Silvia; Herrera, Katya; I. Milagro, Fermín; Sánchez, Juana; de la Garza, Ana Laura; Castro, Heriberto. miRNAs and Novel Food Compounds Related to the Browning Process. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019. DOI: 10.3390/ijms20235998

  • López-Pascual, A.; Urrutia-Sarratea, A.; Lorente-Cebrián, S.; Martínez, J.A.; González-Muniesa, P. Cerium oxide nanoparticles regulate insulin sensitivity and oxidative markers in 3T3-L1 adipocytes and C2C12 myotubes. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2019. DOI: 10.1155/2019/2695289

  • Lorente-Cebrián, Silvia; González-Muniesa, Pedro; Milagro, Fermín i.; Martínez, J. alfredo. MicroRNAs and other non-coding RNAs in adipose tissue and obesity: emerging roles as biomarkers and therapeutic targets. CLINICAL SCIENCE. 2019. DOI: 10.1042/CS20180890

  • Laiglesia, L.M.; Lorente-Cebrián, S.; López-Yoldi, M.; Lanas, R.; Sainz, N.; Martínez, J.A.; Moreno-Aliaga, M.J. Maresin 1 inhibits TNF-alpha-induced lipolysis and autophagy in 3T3-L1 adipocytes. JOURNAL OF CELLULAR PHYSIOLOGY. 2018. DOI: 10.1002/jcp.26096

  • Laiglesia, L.M.; Lorente-Cebrián, S.; Martínez-Fernández, L.; Sáinz, N.; Prieto-Hontoria, P.; Burrell, M.A.; Rodríguez-Ortigosa, C.M.; Martínez, J.A.; Moreno-Aliaga, M.J. Maresin 1 mitigates liver steatosis in ob/ob and diet-induced obese mice. INTERNATIONAL JOURNAL OF OBESITY. 2018. DOI: 10.1038/ijo.2017.226

  • de Gregori, Manuela; Belfer, Inna; de Giorgio, Roberto; Marchesini, Maurizio; Muscoli, Carolina; Rondanelli, Mariangela; Martini, Daniela; Mena, Pedro; Arranz, Laura Isabel; Lorente-Cebrián, Silvia; Perna, Simone; Villarini, Anna; Salamone, Maurizio; Allegri, Massimo; Schatman, Michael E. Second edition of SIMPAR’s “Feed Your Destiny” workshop: the role of lifestyle in improving pain management. JOURNAL OF PAIN RESEARCH. 2018. DOI: 10.2147/JPR.S160660

  • Laiglesia, L.M.; Lorente-Cebrián, S.; Prieto-Hontoria, P.L.; Fernández-Galilea, M.; Ribeiro, S.M.R.; Sáinz, N.; Martínez, J.A.; Moreno-Aliaga, M.J. Eicosapentaenoic acid promotes mitochondrial biogenesis and beige-like features in subcutaneous adipocytes from overweight subjects. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2016. DOI: 10.1016/j.jnutbio.2016.07.019

  • de Gregori, Manuela; Muscoli, Carolina; Schatman, Michael; Stallone, Tiziana; Intelligente, Fabio; Rondanelli, Mariangela; Franceschi, Francesco; Arranz, Laura I; Lorente Cebrián, Silvia; Salamone, Maurizio; Ilari, Sara; Belfer, Inna; Allegri, Massimo. Combining pain therapy with lifestyle: the role of personalized nutrition and nutritional supplements according to the SIMPAR Feed Your Destiny approach. JOURNAL OF PAIN RESEARCH. 2016. DOI: 10.2147/JPR.S115068

  • Lorente-Cebrián, Silvia; Costa, André G.V.; Navas-Carretero, Santiago; Zabala, María; Laiglesia, Laura M.; Martínez, J. Alfredo; Moreno-Aliaga, María J. An update on the role of omega-3 fatty acids on inflammatory and degenerative diseases. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2015. DOI: 10.1007/s13105-015-0395-y

  • Belarbi, Yasmina; Mejhert, Niklas; Lorente-Cebrián, Silvia; Dahlman, Ingrid; Arner, Peter; Rydén, Mikael; Kulyté, Agné. MicroRNA-193b Controls Adiponectin Production in Human White Adipose Tissue. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2015. DOI: 10.1210/jc.2015-1530

  • Kulyté, A.; Lorente-Cebrián, S.; Gao, H.; Mejhert, N.; Agustsson, T.; Arner, P.; Rydén, M.; Dahlman, I. MicroRNA profiling links miR-378 to enhanced adipocyte lipolysis in human cancer cachexia. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2014. DOI: 10.1152/ajpendo.00249.2013

  • Gao, H;Mejhert, N.; Fretz, Ja.; Arner, E.; Lorente-Cebrián, S.; Ehrlund, A.; Dahlman-Wright, K.; Gong, X.; Strömblad, S.; Douagi, I;Laurencikiene, J.; Dahlman, I.; Daub, Co.; Rydén, M.; Horowitz, Mc.; Arner, P. Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue. CELL METABOLISM. 2014. DOI: 10.1016/j.cmet.2014.03.032

  • Lorente-Cebrián, S; Mejhert, N; Kulyté, A; Laurencikiene, J; Aström, G; Hedén, P; Rydén, M; Arner, P. MicroRNAs regulate human adipocyte lipolysis: effects of miR-145 are linked to TNF-a. PLOS ONE. 2014. DOI: 10.1371/journal.pone.0086800

  • Kulyté, A;Belarbi, Y;Lorente-Cebrián, S;Bambace, C;Arner, E;Daub, Co;Hedén, P;Rydén, M;Mejhert, N;Arner, P. Additive effects of miRNAs and transcription factors on CCL2 production in human white adipose tissue. DIABETES. 2014. DOI: 10.2337/db13-0702

  • Lorente-Cebrián, S.; Decaunes, P.; Dungner, E.; Bouloumié, A.; Arner, P.; Dahlamn, I. Allograft inflammatory factor 1 (AIF-1) is a new human adipokine involved in adipose inflammation in obese women. BMC ENDOCRINE DISORDERS. 2013. DOI: 10.1186/1472-6823-13-54

  • Ehrlund, A.; Mejhert, N.; Lorente-Cebrián, S.; Aström, G.; Dahlman, I.; Laurencikiene, J.; Rydén, M. Characterization of the Wnt inhibitors secreted frizzled-related proteins (SFRPs) in human adipose tissue. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2013. DOI: 10.1210/jc.2012-3416

  • Pettersson, Am;Stenson, Bm;Lorente-Cebrián, S;Andersson, D;Mejhert, N;Krätzel, J;Aström, G;Dahlman, I;Chibalin, Av;Arner, P;Laurencikiene, J. LXR is a negative regulator of glucose uptake in human adipocytes. DIABETOLOGIA. 2013. DOI: 10.1007/s00125-013-2954-5

  • Lorente-Cebrián, Silvia; Costa, André G. V.; Navas-Carretero, Santiago; Zabala, María; Martínez, J. Alfredo; Moreno-Aliaga, María J. Role of omega-3 fatty acids in obesity, metabolic syndrome, and cardiovascular diseases: a review of the evidence. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2013. DOI: 10.1007/s13105-013-0265-4

  • Lorente-Cebrián, S; Bustos, M; Marti, A; Fernández-Galilea, M; Martinez, Ja; Moreno-Aliaga, Mj. Eicosapentaenoic acid inhibits tumour necrosis factor-?-induced lipolysis in murine cultured adipocytes. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2012. DOI: 10.1016/j.jnutbio.2010.11.018

  • Lorente-Cebrián, S;Eriksson, A;Dunlop, T;Mejhert, N;Dahlman, I;Aström, G;Sjölin, E;Wåhlén, K;Carlberg, C;Laurencikiene, J;Hedén, P;Arner, P;Rydén, M. Differential effects of 1?,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes. EUROPEAN JOURNAL OF NUTRITION. 2012. DOI: 10.1007/s00394-011-0218-z

  • Arner, E;Mejhert, N;Kulyté, A;Balwierz, Pj;Pachkov, M;Cormont, M;Lorente-Cebrián, S;Ehrlund, A;Laurencikiene, J;Hedén, P;Dahlman-Wright, K;Tanti, Jf;Hayashizaki, Y;Rydén, M;Dahlman, I;Van Nimwegen, E;Daub, Co;Arner, P. Adipose tissue microRNAs as regulators of CCL2 production in human obesity. DIABETES. 2012. DOI: 10.2337/db11-1508

  • Axelsson, J; Aström, G; Sjölin, E; Qureshi, Ar; Lorente-Cebrián, S; Stenvinkel, P; Rydén, M. Uraemic sera stimulate lipolysis in human adipocytes: role of perilipin. NEPHROLOGY DIALYSIS TRANSPLANTATION. 2011. DOI: 10.1093/ndt/gfq755

  • Lorente-Cebrián, S;Kulyté, A;Hedén, P;Näslund, E;Arner, P;Rydén, M. Relationship between site-specific HSL phosphorylation and adipocyte lipolysis in obese women. OBESITY FACTS. 2011. DOI: 10.1159/000334036

  • Lorente-Cebrián, S.; Bustos, M.; Marti, A.; Martinez, Ja.; Moreno-Aliaga, Mj. Eicosapentaenoic acid up-regulates apelin secretion and gene expression in 3T3-L1 adipocytes. MOLECULAR NUTRITION & FOOD RESEARCH. 2010. DOI: 10.1002/mnfr.200900522

  • Moreno-Aliaga, María J.; Lorente-Cebrián, Silvia; Martínez, J. Alfredo. Regulation of adipokine secretion byn-3 fatty acids. PROCEEDINGS OF THE NUTRITION SOCIETY. 2010. DOI: 10.1017/S0029665110001801

  • Lorente-Cebrián, S.; Bustos, M.; Marti, A.; Martinez, Ja.; Moreno-Aliaga, Mj. Eicosapentaenoic acid stimulates AMP-activated protein kinase and increases visfatin secretion in cultured murine adipocytes. CLINICAL SCIENCE. 2009. DOI: 10.1042/CS20090020

  • Moreno-Aliaga, Mj; Swarbrick, Mm; Lorente-Cebrián, S; Stanhope, Kl; Havel, P; Martínez, Ja. Sp1-mediated transcription is involved in the induction of leptin by insulin-stimulated glucose metabolism. JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2007. DOI: 10.1677/JME-06-0034

  • Wood, Is.; Wang, B.; Lorente-Cebrián, S.; Trayhurn, P. Hypoxia increases expression of selective facilitative glucose transporters (GLUT) and 2-deoxy-D-glucose uptake in human adipocytes. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007. DOI: 10.1016/j.bbrc.2007.07.032

  • Lorente-Cebrián, S.; Pérez-Matute, P.; Martínez, Ja.; Marti, A.; Moreno-Aliaga, Mj. Effects of eicosapentaenoic acid (EPA) on adiponectin gene expression and secretion in primary cultured rat adipocytes. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2006. DOI: 10.1007/BF03174067

Capítulos

  • Acciones de los ácidos grasos poliinsaturados omega-3 y mediadores lipídicos derivados en obesidad e inflamación: regulación de la secreción de adipoquinas. Lorente Cebrián, Silvia; Laiglesia, Laura M.; Martínez, J. Alfredo; Moreno Aliaga, María Jesús. INMUNONUTRICIÓN. ESTILO DE VIDA. 2019

  • M. J. Moreno Aliaga, S. Lorente Cebrián y J. Alfredo Martínez. Regulación de la secreción de adipoquinas por los ácidos grasos poliinsaturados n-3*. INMUNONUTRICIÓN: EN LA SALUD Y LA ENFERMEDAD. 2011

  • M. Fernández Galilea, S. Lorente Cebrián y M. J. Moreno Aliaga. Determinación de los niveles plasmáticos de la leptina e insulina. FUNDAMENTOS DE NUTRICIÓN Y DIETÉTICA: BASES METODOLÓGICAS Y APLICACIONES. 2010

  • P. Pérez Matute, S. Lorente Cebrián y M. J. Moreno Aliaga. Adipocitos y adipoquinas: cultivo primario de adipocitos de rata. FUNDAMENTOS DE NUTRICIÓN Y DIETÉTICA: BASES METODOLÓGICAS Y APLICACIONES. 2010

  • S. Lorente Cebrián, M. Zabala Navó y M. J. Moreno Aliaga. Actividad glutación reductasa eritrocitaria como indicador en estados de deficiencia de vitamina B2. FUNDAMENTOS DE NUTRICIÓN Y DIETÉTICA: BASES METODOLÓGICAS Y APLICACIONES. 2010



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